NFL San Francisco 49ers Week 17 predictions: Can the 49ers upset the Lions? Fans weigh in Michael A. De Leon December 28, 2024 Share on Facebook Share on Twitter Send via Email The San Francisco 49ers are set to host the Detroit Lions at Levi’s Stadium in Santa Clara, California, on Monday, December 30, at 5:15 p.m. PT. The Lions enter the contest as 3.5-point favorites. What do you feel about this? 0% Love 0% Funny 0% Wow 0% Sad 0% Angry Share on Facebook Share on Twitter Send via Email Post navigation Previous: Watch: Trey McBride scores first receiving touchdown after breaking unwanted recordNext: Jansen urges SA to be ‘disciplined’ as WTC final beckons More Stories Dallas Cowboys NFL Greg Olsen Questions Cowboys’ Run-First Approach With Dak Prescott At QB Megan Armstrong November 13, 2026 NFL San Francisco 49ers 49ers’ Kyle Shanahan Stunned By FAA Ground Stop News Ahead Of Cowboys Clash Michael A. De Leon November 13, 2026 Las Vegas Raiders NFL Raiders Turned Down Interest In DE Maxx Crosby Jeph Duarte November 13, 2026 Dallas Cowboys NFL Dallas Cowboys Make Major Change Before 49ers Game Megan Armstrong November 13, 2026 Dallas Cowboys NFL San Francisco 49ers Stephen A. Smith Predicts Cowboys Loss, Warns 49ers Upset Would Set Up Fall Michael A. De Leon November 13, 2026 Las Vegas Raiders NFL Raiders Nearly Delayed Fernando Mendoza Era Before Trading Kirk Cousins to Vikings Jeph Duarte November 13, 2026 Leave a Reply Cancel replyYou must be logged in to post a comment.