NFL San Francisco 49ers Brock Purdy likely out for Week 6; Mac Jones expected to start Michael A. De Leon October 9, 2025 It appears that 49ers quarterback Brock Purdy‘s toe injury will force him to sit out again this week. Purdy did not practice on Thursday, setting up backup Mac Jones to start against the Buccaneers on Sunday, Adam Schefter of ESPN reports. Post navigation Previous: Jaxson Dart, Cam Skattebo power Giants to dominant win over EaglesNext: The Trump Administration Is Hiding How Many Pregnant People Are in ICE Detention More Stories Los Angeles Rams NFL NFC Notes: Matthew Stafford, Mack Wilson, Cardinals, Rams, Seahawks K Kearney May 19, 2026 NFL San Francisco 49ers NFL insider offers blunt advice to 49ers WR Brandon Aiyuk Michael A. De Leon May 19, 2026 Jacksonville Jaguars NFL AFC Notes: DaVon Hamilton, Woody Marks, Jaguars, Texans, Titans Isaac Gutierrez May 19, 2026 NFL Tampa Bay Buccaneers NFC Notes: Bucky Irving, Tyler Shough, Buccaneers, Panthers, Saints Kyle Newport May 19, 2026 NFL San Francisco 49ers 49ers projected to return to playoffs in two NFL.com predictions Michael A. De Leon May 19, 2026 Los Angeles Rams NFL Sean McVay makes admission about past retirement rumors K Kearney May 19, 2026 Leave a Reply Cancel replyYou must be logged in to post a comment.